Immune-Based Therapies

Immune-Based Therapies

(See also: HIV and the Immune System; Interleukin-2; Monoclonal Antibodies; Vaccines to Prevent or Treat HIV Infection)


Immune restoration. Fact sheet from AIDS InfoNet. Also available in Spanish.

Immune therapies in development. Fact sheet from AIDS InfoNet. Also available in Spanish.

Immune-Based Therapies. Fact sheet from aidsmeds.com.

Strategies for improving immune health.  Fact sheet from Project Inform.  Also available in Spanish

Interleukin-2.  Fact sheet from AIDS Infonet. Also available in Spanish.

Aralen (chloroquine phosphate).  Fact sheet from aidsmeds.com.

DermaVir (therapeutic vaccine). Fact sheet from aidsmeds.com.

IL-7 (IL-7). Fact sheet from aidsmeds.com.

Ibalizumab. Fact sheet from aidsmeds.com. 

Lexgenleucel-T (VRX-496; gene therapy). Fact sheet from aidsmeds.com.

Plaquenil (hydroxychloroquine) .  Fact sheet from aidsmeds.com.
 
Proleukin (aldesleukin, Interleukin-2, or IL-2).  Fact sheet from aidsmeds.com. 

SB-728-T (gene therapy). Fact sheet from aidsmeds.com.

Vacc-4x (therapeutic vaccine). Fact sheet from aidsmeds.com.

Passive immunotherapy.  Definition from AIDSinfo glossary.


Selected Recent Articles

Targeted T-cells Derived from Engineered Stem Cells Reduce HIV Viral Load in Mice. Article dated April 20, 2012 from hivandhepatitis.com.

CROI: The Long and Winding Road to a Cure for HIV. Article dated April 13, 2012 from hivandhepatitis.com.

Engineering CD8 Cells to Kill HIV in Tissues. Article dated April 13, 2012 from aidsmeds.com.

Toward a Cure: The Potential of Therapeutic Vaccines. Article dated April 10, 2012 from aidsmeds.com.

HIV Vaccine Study Offers Up Possible Antibody Protection Clues. Article dated April 9, 2012 from aidsmeds.com.

Zinc Finger HIV Gene Therapy Moves Ahead. Article dated March 27, 2012 from hivandhepatitis.com.

CROI: Vorinostat -- A First Step on the Road Towards a Cure for HIV. Article dated March 16, 2012 from hivandhepatitis.com.

Pathway to a Cure: Cancer Drug Helps Purge HIV From Resting Cells. Article dated March 9, 2012 from aidsmeds.com.

Pathway to a Cure: Positive Results Continue for Sangamo’s CCR5 Gene Therapy. Article dated March 9, 2012 from aidsmeds.com.

CROI: HIV Cure Research -- A New Era of Treatment. Article dated March 9, 2012 from hivandhepatitis.com.

The Path to a Cure. Article dated January/February 2012 from Positively Aware.

Sangamo HIV Gene Therapy Trials: Until There's A Functional Cure, Treatment! Article dated January 19, 2012 from hivandhepatitis.com.

New Studies Under Way of Sangamo's Possible 'Functional Cure' Gene Therapy. Article dated January 10, 2012 from aidsmeds.com.

Advances in CCR5 Gene Therapy Give New Hope for HIV Cure. Article dated November 29, 2011 from aidsmeds.com.

Immunisation doesn't prevent mother-to-child HIV transmissions, but approach should not be abandoned, says expert. Article dated November 15, 2011 from aidsmap.com.

Cholesterol-depleted HIV Triggers Adaptive Immune Response.  Article dated September 30, 2011 from hivandhepatitis.com.

HIV Antibody Therapy Ibalizumab Inches Forward. Article dated September 27, 2011 from aidsmeds.com.

Sangamo's Gene Therapy Continues to Show Well in Study. Article dated September 21, 2011 from aidsmeds.com.

Gene therapy for HIV is “progress towards functional cure” say researchers. Article dated September 20, 2011 from aidsmap.com.

ICAAC: Zinc Finger Gene Therapy Boosts CD4 Cells, May Lower HIV Viral Load. Article dated September 20, 2011 from hivandhepatitis.com.

Preventive and Therapeutic HIV Vaccine Data Presented at AIDS Vaccine 2011. Article dated September 19, 2011 from hivandhepatitis.com.

Gene Therapy Protects Cat Cells against Feline Immunodeficiency Virus. Article dated September 13, 2011 from hivandhepatitis.com.

Researchers Discover How HIV Neutralizing Antibodies Evolve. Article dated August 17, 2011 from hivandhepatitis.com.

Gene Therapy Using Modified HIV Hailed as Potential Cancer Cure. Article dated August 12, 2011 from hivandhepatitis.com.

Researchers Reverse HIV-Related B-Cell Exhaustion. Article dated June 7, 2011 from hivandhepatitis.com.

CROI 2011. See the section, “New gene therapy proves safe, effective.” Article dated May/June 2011 from Positively Aware.

Researchers Explore Agents that Reduce CD4 Cell Reservoir and Activate Latent HIV.  Article dated April 29, 2011 from hivandhepatitis.com.

Researchers Discover How TRIM5 Protects against HIV.  Article dated April 26, 2011 from hivandhepatitis.com.

Gold Drug Shows HIV Eradication Potential.  Article dated April 21, 2011 from aidsmeds.com.

Gold-based drug shows promise in clearing HIV reservoir in monkey study.  Article dated April 20, 2011 from aidsmap.com.

No More Science Fiction: HIV Gene Therapy Delivers. Article dated March 4, 2011 from hivandhepatitis.com.

Promising New Gene Therapy for HIV Immunity. Article dated March 3, 2011 from CDC's HIV/Hepatitis/STD/TB Prevention News Update.

Zinc Fingers and Gene Therapies for HIV: Mimicking the Cured Berlin Patient?  Article dated March 2, 2011 from The Body Pro website.

Zinc finger gene therapy produces HIV-resistant CD4 T-cells. Article dated March 1, 2011 from aidsmap.com.

Gene Therapy Makes Small but Promising Early Steps Forward as Potential Form of HIV Treatment. Article dated March 1, 2011 from The Body Pro website.

New Cure-Related Research: Antabuse to Flush HIV Reservoir. Article dated February 8, 2011 from aidsmeds.com.

"Berlin Patient" Still HIV-free 4 Years after Bone Marrow Transplant. Article dated December 14, 2010 from hivandhepatitis.com.

Stem cell transplant has cured HIV infection in 'Berlin patient', say doctors. Article dated December 13, 2010 from aidsmap.com.

Berlin Patient Follow-Up 'Strongly Suggests' HIV Cure. Article dated December 10, 2010 from aidsmeds.com.

Protein Discovery Helps Explain the Body's Failure to Kill HIV. Article dated November 19, 2010 from aidsmeds.com.

HIV Antibodies Do Control Infection: New Hope for Vaccines and Treatment.  Article dated October 25, 2010 from aidsmeds.com.

New HIV Eradication Study in Progress.  Article dated October 20, 2010 from aidsmeds.com.

One on One: Sharon Lewin discusses emerging strategies in cure research. Article from the September/October 2010 issue of Positively Aware.

Renewed hope: Efforts to discover a cure for HIV take on a new life -- but it still won’t be easy. Article from the September/October 2010 issue of Positively Aware.

Getting closer: Studies take aim at eradicating the virus. Article dated September/October 2010 issue of Positively Aware.

AIDS Cure Research: North Carolina Scientist Study Cancer Drug. Article dated September 3, 2010 from aidsmeds.com.

New Strategy Could Eradicate Latent HIV-Infected Cells. Article dated August 19, 2010 from aidsmeds.com.

The Alphabet Soup of Immune Control: ADCC Antibodies, (Memory) B-Cells, Elite Controllers and Exposed Sero-Negatives -- Will They Amount to Z? Article dated July 23, 2010 from thebody.com.

Natural Killer Cells Are Prominent Factors in Control of HIV. Article dated July 22, 2010 from thebody.com.

Protective Genes Play Crucial Role in Defense Against HIV. Article dated July 21, 2010 from thebody.com.

Argos's Dendritic Cell Therapy Reduces HIV During Treatment Interruption. Article dated July 19, 2010 from aidsmeds.com.

New Role for HIV Protease Inhibitors?  Article dated June 11, 2010 from aidsmeds.com.

New Therapy Shows Potential as an Anti-HIV Medication. Article dated April 9, 2010 from aidsmeds.com.

Researchers Announce New HIV-Silencing Stem Cell Therapy. Article dated April 1, 2010 from aidsmeds.com.

Coming down the line.  Article from the March/April 2010 issue of Positively Aware.

No Benefit From Cyclosporine During Early Infection. Article dated March 18, 2010 from aidsmeds.com.

Targeting Hidden HIV: Research Group Licenses New Prostratin Technology. Article dated February 8, 2010 from aidsmeds.com.

New Technology Finds Meds That Might Flush Out Hidden HIV Reservoirs.  Article dated October 2, 2009 from aidsmeds.com. 

IL-7 may boost CD4 and CD8 T-cells, study shows.  Article dated September 17, 2009 from aidsmap.com. 

Scientists Discover Antibodies That Halt HIV Disease Progression.  Article dated September 4, 2009 from aidsmeds.com. 

New antibodies identified that neutralise wide range of HIV types.  Article dated September 3, 2009 from aidsmap.com. 

A New Simpler Gene Therapy for HIV.  Article dated September 3, 2009 from aidsmeds.com. 

New Technology Finds Meds That Might Flush Out Hidden HIV Reservoirs.  Article dated October 2, 2009 from aidsmeds.com.

 

IL-7 may boost CD4 and CD8 T-cells, study shows.  Article dated September 17, 2009 from aidsmap.com.

 

Scientists Discover Antibodies That Halt HIV Disease Progression.  Article dated September 4, 2009 from aidsmeds.com.

 

A New Simpler Gene Therapy for HIV.  Article dated September 3, 2009 from aidsmeds.com.

 

New antibodies identified that neutralise wide range of HIV types.  Article dated September 3, 2009 from aidsmap.com. 

New Research Shows Why Antibodies Fail to Control HIV.  Article dated April 23, 2009 from aidsmeds.com.

Big Leap Forward in HIV Vaccine Science.  Article dated March 13, 2009 from aidsmeds.com.

Treating HIV and cancer with radioimmunotherapy. Article dated February 27, 2009 from aidsmeds.com.

Interleukin-2 shows no benefit in two large clinical trials. Article dated February 10, 2009 from aidsmap.com.

IL-2 fails in two large studies. Article dated February 10, 2009 from aidsmeds.com.

Martin Delaney: An AIDS Warrior Passes the Torch.  Article dated January 27, 2009 from aidsmeds.com.

IL-2 provides quick ‘AIDS rescue’, but effect does not always last. Article dated November 17, 2008 from aidsmap.com.

Vaccines, Lessons Learned.  Article dated September 24, 2008 from aidsmeds.com.

Future Options for the Treatment Experienced.  Article dated September 24, 2008 from aidsmeds.com.

A 'functional cure' for HIV? Article dated September 9, 2008 from aidsmeds.com.

Vaccines: Lessons Learned.  Article dated August 18, 2008 from aidsmeds.com.

Future Options for the Treatment Experienced.  Article dated August 12, 2008 from aidsmeds.com.

Two novel immune therapies in early investigation: autologous dendritic cells and CD4 zeta gene-modified T cells. Article dated August 7, 2008 from aidsmap.com.

Slowing CD4 cell decline with IL-2 allows HIV treatment to be deferred by 92 weeks. Article dated August 6, 2008 from aidsmap.com.

Loreen Willenberg: In Search of (Other) HIV Controllers.  Article dated July 22, 2008 from aidsmeds.com.

Scientists Discover and Target HIV's Weak Spot.  Article dated July 16, 2008 from aidsmeds.com.

Therapeutic Vaccine Tanks in Study.  Article dated July 11, 2008 from aidsmeds.com.

Therapeutic’ HIV vaccine leads to higher viral load, less time off treatment.  Article dated July 10, 2008 from aidsmap.com.
 
Stimulated cells control SIV, and hopefully HIV. Article dated May 5, 2008 from aidsmeds.com.

Interfering with Immune Protein Slows HIV Reproduction.  Article dated April 29, 2008 from aidsmeds.com.

HIV immunotherapy shows promise. Article dated April 16, 2008 from aidsmeds.com.

New way of attacking HIV looks promising in early trial.  Article dated March 25, 2008 from aidsmap.com.

Increases in CD4 cell counts seen with growth hormone, interleukin-7. Article dated March 6, 2008 from aidsmap.com.

Growth hormone boosts thymus T-cell production. Article dated February 25, 2008 from aidsmeds.com.

VIRxSYS Gene Therapy Makes Progress.  Article dated February 12, 2008 from aidsmeds.com. 

A New Approach: Immune-Based Treatments Against HIV.  Article from the May/June issue of Positively Aware.


 

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